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Vectors for Human PTPN11

Gene Information

  • Offical Gene Symbol PTPN11
  • Species Human (Homo sapiens)
  • Offical Full Name protein tyrosine phosphatase non-receptor type 11
  • Other Aliases BPTP3; CFC; JMML; METCDS; NS1; PTP-1D; PTP2C; SH-PTP2; SH-PTP3; SHP2
  • Other Desigations tyrosine-protein phosphatase non-receptor type 11; SH2 domain-containing protein tyrosine phosphatase 2; protein-tyrosine phosphatase 1D; protein-tyrosine phosphatase 2C
  • Gene Type protein-coding
  • Summary
    The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. [provided by RefSeq, Aug 2016]
  • NCBI Gene ID 5781
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human PTPN11(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PTPN11 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human PTPN11 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human PTPN11 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human PTPN11 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human PTPN11 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PTPN11 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human PTPN11 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human PTPN11 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human PTPN11 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PTPN11 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human PTPN11 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human PTPN11 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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