Vectors for Human RASGRF1

Gene Information

  • Offical Gene Symbol RASGRF1
  • Species Human (Homo sapiens)
  • Offical Full Name Ras protein specific guanine nucleotide releasing factor 1
  • Other Aliases CDC25; CDC25L; GNRP; GRF1; GRF55; H-GRF55; PP13187; ras-GRF1
  • Other Desigations ras-specific guanine nucleotide-releasing factor 1; CDC25 like; Ras-specific guanine nucleotide-releasing factor, CDC25 homolog; Ras-specific nucleotide exchange factor CDC25; guanine nucleotide exchange factor; guanine nucleotide-releasing factor 1; guanine nucleotide-releasing factor, 55 kD; guanine nucleotide-releasing protein
  • Gene Type protein-coding
  • Summary
    The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Mar 2009]
  • NCBI Gene ID 5923
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human RASGRF1(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human RASGRF1 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human RASGRF1 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human RASGRF1 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human RASGRF1 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human RASGRF1 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human RASGRF1 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human RASGRF1 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human RASGRF1 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human RASGRF1 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human RASGRF1 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human RASGRF1 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human RASGRF1 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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