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Vectors for Human SCN7A

Gene Information

  • Offical Gene Symbol SCN7A
  • Species Human (Homo sapiens)
  • Offical Full Name sodium voltage-gated channel alpha subunit 7
  • Other Aliases NaG; Nav2.1; Nav2.2; SCN6A
  • Other Desigations sodium channel protein type 7 subunit alpha; putative voltage-gated sodium channel subunit alpha Nax; sodium channel protein cardiac and skeletal muscle subunit alpha; sodium channel protein type VII subunit alpha; sodium channel, voltage-gated, type VI, alpha polypeptide; sodium channel, voltage-gated, type VII, alpha subunit; voltage-dependent sodium channel alpha subunit
  • Gene Type protein-coding
  • Summary
    This gene encodes one of the many voltage-gated sodium channel proteins. For proper functioning of neurons and muscles during action potentials, voltage-gated sodium channels direct sodium ion diffusion for membrane depolarization. This sodium channel protein has some atypical characteristics; the similarity between the human and mouse proteins is lower compared to other orthologous sodium channel pairs. Also, the S4 segments, which sense voltage changes, have fewer positive charged residues that in other sodium channels; domain 4 has fewer arginine and lysine residues compared to other sodium channel proteins. Several alternatively spliced transcript variants exist, but the full-length natures of all of them remain unknown. [provided by RefSeq, Dec 2011]
  • NCBI Gene ID 6332
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNC |  UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Human SCN7A(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SCN7A expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Human SCN7A expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Human SCN7A expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Human SCN7A expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Human SCN7A expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SCN7A shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide 
$149
View Vector 
Human SCN7A shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide 
$299
View Vector 
Human SCN7A shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide 
$149
View Vector 
Human SCN7A shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide 
$149
View Vector 
CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SCN7A CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide 
$149
View Vector 
Human SCN7A CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide 
$149
View Vector 
Human SCN7A CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide 
$299
View Vector 

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