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Vectors for Human TAX1BP3

Gene Information

  • Offical Gene Symbol TAX1BP3
  • Species Human (Homo sapiens)
  • Offical Full Name Tax1 binding protein 3
  • Other Aliases TIP-1; TIP1
  • Other Desigations tax1-binding protein 3; Tax interaction protein 1; Tax1 (human T-cell leukemia virus type I) binding protein 3; glutaminase-interacting protein 3; tax-interacting protein 1
  • Gene Type protein-coding
  • Summary
    This gene encodes a small, highly conserved protein with a single PDZ domain. PDZ (PSD-95/Discs large/ZO-1 homologous) domains promote protein-protein interactions that affect cell signaling, adhesion, protein scaffolding, and receptor and ion transporter functions. The encoded protein interacts with a large number of target proteins that play roles in signaling pathways; for example, it interacts with Rho A and glutaminase L and also acts as a negative regulator of the Wnt/beta-catenin signaling pathway. This protein was first identified as binding to the T-cell leukaemia virus (HTLV1) Tax oncoprotein. Overexpression of this gene has been implicated in altered cancer cell adhesion, migration and metastasis. The encoded protein also modulates the localization and density of inwardly rectifying potassium channel 2.3 (Kir2.3). To date, this protein has been shown to play a role in cell proliferation, development, stress response, and polarization. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Apr 2017]
  • NCBI Gene ID 30851
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNC |  UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Human TAX1BP3(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human TAX1BP3 expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Human TAX1BP3 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Human TAX1BP3 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Human TAX1BP3 expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Human TAX1BP3 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human TAX1BP3 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide 
$149
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Human TAX1BP3 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide 
$299
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Human TAX1BP3 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide 
$149
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Human TAX1BP3 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide 
$149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human TAX1BP3 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide 
$149
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Human TAX1BP3 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide 
$149
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Human TAX1BP3 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide 
$299
View Vector 

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