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Vectors for Human UACA

Gene Information

  • Offical Gene Symbol UACA
  • Species Human (Homo sapiens)
  • Offical Full Name uveal autoantigen with coiled-coil domains and ankyrin repeats
  • Other Aliases NUCLING
  • Other Desigations uveal autoantigen with coiled-coil domains and ankyrin repeats; nuclear membrane binding protein
  • Gene Type protein-coding
  • Summary
    This gene encodes a protein that contains ankyrin repeats and coiled coil domains and likely plays a role in apoptosis. Studies in rodents have implicated the encoded protein in the stimulation of apoptosis and the regulation of mammary gland involution, in which the mammary gland returns to its pre-pregnant state. This protein has also been proposed to negatively regulate apoptosis based on experiments in human cell lines in which the protein was shown to interact with PRKC apoptosis WT1 regulator protein, also known as PAR-4, and inhibit translocation of the PAR-4 receptor. Autoantibodies to this protein have been identified in human patients with panuveitis and Graves\' disease. Differential expression of this gene has been observed in various human cancers. [provided by RefSeq, May 2017]
  • NCBI Gene ID 55075
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human UACA(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human UACA expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human UACA expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human UACA expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human UACA expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human UACA expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human UACA shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human UACA shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human UACA shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human UACA shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human UACA CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human UACA CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human UACA CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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