Vectors for Human UBE4A

Gene Information

  • Offical Gene Symbol UBE4A
  • Species Human (Homo sapiens)
  • Offical Full Name ubiquitination factor E4A
  • Other Aliases E4; NEDHMS; UBOX2; UFD2
  • Other Desigations ubiquitin conjugation factor E4 A; RING-type E3 ubiquitin transferase E4 A; ubiquitination factor E4A (UFD2 homolog, yeast)
  • Gene Type protein-coding
  • Summary
    This gene encodes a member of the U-box ubiquitin ligase family. The encoded protein is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn\'s disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011]
  • NCBI Gene ID 9354
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human UBE4A(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human UBE4A expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human UBE4A expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human UBE4A expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human UBE4A expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human UBE4A expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human UBE4A shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human UBE4A shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human UBE4A shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human UBE4A shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human UBE4A CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human UBE4A CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human UBE4A CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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