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Vectors for Human UBE4B

Gene Information

  • Offical Gene Symbol UBE4B
  • Species Human (Homo sapiens)
  • Offical Full Name ubiquitination factor E4B
  • Other Aliases E4; HDNB1; UBOX3; UFD2; UFD2A
  • Other Desigations ubiquitin conjugation factor E4 B; RING-type E3 ubiquitin transferase E4 B; homologous to yeast UFD2; homozygously deleted in neuroblastoma-1; ubiquitin-fusion degradation protein 2; ubiquitination factor E4B (UFD2 homolog, yeast)
  • Gene Type protein-coding
  • Summary
    The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • NCBI Gene ID 10277
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human UBE4B(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human UBE4B expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human UBE4B expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human UBE4B expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human UBE4B expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human UBE4B expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human UBE4B shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human UBE4B shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human UBE4B shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human UBE4B shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human UBE4B CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human UBE4B CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human UBE4B CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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