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Vectors for Human UCMA

Gene Information

  • Offical Gene Symbol UCMA
  • Species Human (Homo sapiens)
  • Offical Full Name upper zone of growth plate and cartilage matrix associated
  • Other Aliases C10orf49; GRP; GRP/UCMA
  • Other Desigations unique cartilage matrix-associated protein; Gla-rich protein
  • Gene Type protein-coding
  • Summary
    This gene encodes a chondrocyte-specific, highly charged protein that is abundantly expressed in the upper immature zone of fetal and juvenile epiphyseal cartilage. The encoded protein undergoes proteolytic processing to generate a mature protein that is secreted into the extracellular matrix. The glutamic acid residues in the encoded protein undergo gamma carboxylation in a vitamin K-dependent manner. Undercarboxylation of the encoded protein is associated with osteoarthritis in humans. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2015]
  • NCBI Gene ID 221044
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human UCMA(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human UCMA expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human UCMA expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human UCMA expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human UCMA expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human UCMA expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human UCMA shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
View Vector 
Human UCMA shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
View Vector 
Human UCMA shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human UCMA shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human UCMA CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
View Vector 
Human UCMA CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human UCMA CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
View Vector 

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