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Vectors for Human UHRF1

Gene Information

  • Offical Gene Symbol UHRF1
  • Species Human (Homo sapiens)
  • Offical Full Name ubiquitin like with PHD and ring finger domains 1
  • Other Aliases ICBP90; Np95; RNF106; TDRD22; hNP95; hUHRF1; huNp95
  • Other Desigations E3 ubiquitin-protein ligase UHRF1; RING finger protein 106; RING-type E3 ubiquitin transferase UHRF1; inverted CCAAT box binding protein 90; inverted CCAAT box-binding protein of 90 kDa; nuclear phosphoprotein 95; nuclear protein 95; nuclear zinc finger protein Np95; transcription factor ICBP90; ubiquitin-like PHD and RING finger domain-containing protein 1
  • Gene Type protein-coding
  • Summary
    This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. It is regarded as a hub protein for the integration of epigenetic information. This gene is up-regulated in various cancers, and it is therefore considered to be a therapeutic target. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene exists on chromosome 12. [provided by RefSeq, Feb 2014]
  • NCBI Gene ID 29128
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNC |  UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Human UHRF1(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human UHRF1 expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Human UHRF1 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Human UHRF1 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Human UHRF1 expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Human UHRF1 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human UHRF1 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide 
$149
View Vector 
Human UHRF1 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide 
$299
View Vector 
Human UHRF1 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide 
$149
View Vector 
Human UHRF1 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide 
$149
View Vector 
CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human UHRF1 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide 
$149
View Vector 
Human UHRF1 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide 
$149
View Vector 
Human UHRF1 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide 
$299
View Vector 

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