Human WRN (Gene ID: 7486) vectors - Lentivirus, AAV, shRNA & CRISPR I VectorBuilder

Gene Information

Offical Gene Symbol WRN
Species Human (Homo sapiens)
Offical Full Name WRN RecQ like helicase
Other Aliases RECQ3; RECQL2; RECQL3
Other Desigations bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN; DNA helicase, RecQ-like type 3; Werner syndrome ATP-dependent helicase; Werner syndrome RecQ like helicase; Werner syndrome protein; Werner syndrome, RecQ helicase-like; exonuclease WRN; recQ protein-like 2
Gene Type protein-coding
Summary
This gene encodes a member of the RecQ subfamily of DNA helicase proteins. The encoded nuclear protein is important in the maintenance of genome stability and plays a role in DNA repair, replication, transcription and telomere maintenance. This protein contains a N-terminal 3\' to 5\' exonuclease domain, an ATP-dependent helicase domain and RQC (RecQ helicase conserved region) domain in its central region, and a C-terminal HRDC (helicase RNase D C-terminal) domain and nuclear localization signal. Defects in this gene are the cause of Werner syndrome, an autosomal recessive disorder characterized by accelerated aging and an elevated risk for certain cancers. [provided by RefSeq, Aug 2017]
NCBI Gene ID 7486
RefSeq Transcript
NM_000553.6
RefSeq Protein
NP_000544.2
External Links NCBI | OMIM | Ensembl | HGNC | UCSC Genome Browser View
View ORF sequence of this gene »

Vector Description	Vector Type	Price
Human WRN expression regular plasmid vector	Mammalian Gene Expression Vector Guide	From $189
Human WRN expression lentivirus vector	Mammalian Gene Expression Lentiviral Vector Guide	From $189
Human WRN expression adenovirus vector	Mammalian Gene Expression Adenoviral Vector Guide	From $189
Human WRN expression AAV vector	Mammalian Gene Expression AAV Vector Guide	From $189
Human WRN expression PiggyBac vector	Mammalian Gene Expression PiggyBac Vector Guide	From $189

Vector Description	Vector Type	Price
Human WRN shRNA lentivirus vector	Mammalian shRNA Knockdown Lentiviral Vector Guide	$149	View Vector
Human WRN shRNA adenovirus vector	Mammalian shRNA Knockdown Adenoviral Vector Guide	$299	View Vector
Human WRN shRNA AAV vector	Mammalian shRNA Knockdown AAV Vector Guide	$149	View Vector
Human WRN shRNA PiggyBac vector	Mammalian shRNA Knockdown PiggyBac Vector Guide	$149	View Vector

Vector Description	Vector Type	Price
Human WRN CRISPR regular plasmid vector	Mammalian CRISPR Vector (Single gRNA) Guide	$149	View Vector
Human WRN CRISPR lentivirus vector	Mammalian CRISPR Lentiviral Vector (Single gRNA) Guide	$149	View Vector
Human WRN CRISPR adenovirus vector	Mammalian CRISPR Adenoviral Vector (Single gRNA) Guide	$299	View Vector

Use this option to design your vector using our online platform.

You can request cloning & virus packaging services for your vector here.

Use this option to ask our scientists to design your vector for free.

You can also submit other service inquires here, including: