Human WRNIP1 (Gene ID: 56897) vectors - Lentivirus, AAV, shRNA & CRISPR I VectorBuilder

Gene Information

Offical Gene Symbol WRNIP1
Species Human (Homo sapiens)
Offical Full Name WRN helicase interacting protein 1
Other Aliases CFAP93; FAP93; WHIP; bA420G6.2
Other Desigations ATPase WRNIP1; Werner helicase interacting protein 1; putative helicase RUVBL
Gene Type protein-coding
Summary
Werner\'s syndrome is a rare autosomal recessive disorder characterized by accelerated aging that is caused by defects in the Werner syndrome ATP-dependent helicase gene (WRN). The protein encoded by this gene interacts with the exonuclease-containing N-terminal portion of the Werner protein. This protein has a ubiquitin-binding zinc-finger domain in the N-terminus, an ATPase domain, and two leucine zipper motifs in the C-terminus. It has sequence similarity to replication factor C family proteins and is conserved from E. coli to human. This protein likely accumulates at sites of DNA damage by interacting with polyubiquinated proteins and also binds to DNA polymerase delta and increases the initiation frequency of DNA polymerase delta-mediated DNA synthesis. This protein also interacts with nucleoporins at nuclear pore complexes. Two transcript variants encoding different isoforms have been isolated for this gene. [provided by RefSeq, Jul 2012]
NCBI Gene ID 56897
RefSeq Transcript
NM_020135.3; NM_130395.3
RefSeq Protein
NP_064520.2; NP_569079.1
External Links NCBI | OMIM | Ensembl | HGNC | UCSC Genome Browser View
View ORF sequence of this gene »

Vector Description	Vector Type	Price
Human WRNIP1 expression regular plasmid vector	Mammalian Gene Expression Vector Guide	From $189
Human WRNIP1 expression lentivirus vector	Mammalian Gene Expression Lentiviral Vector Guide	From $189
Human WRNIP1 expression adenovirus vector	Mammalian Gene Expression Adenoviral Vector Guide	From $189
Human WRNIP1 expression AAV vector	Mammalian Gene Expression AAV Vector Guide	From $189
Human WRNIP1 expression PiggyBac vector	Mammalian Gene Expression PiggyBac Vector Guide	From $189

Vector Description	Vector Type	Price
Human WRNIP1 shRNA lentivirus vector	Mammalian shRNA Knockdown Lentiviral Vector Guide	$149	View Vector
Human WRNIP1 shRNA adenovirus vector	Mammalian shRNA Knockdown Adenoviral Vector Guide	$299	View Vector
Human WRNIP1 shRNA AAV vector	Mammalian shRNA Knockdown AAV Vector Guide	$149	View Vector
Human WRNIP1 shRNA PiggyBac vector	Mammalian shRNA Knockdown PiggyBac Vector Guide	$149	View Vector

Vector Description	Vector Type	Price
Human WRNIP1 CRISPR regular plasmid vector	Mammalian CRISPR Vector (Single gRNA) Guide	$149	View Vector
Human WRNIP1 CRISPR lentivirus vector	Mammalian CRISPR Lentiviral Vector (Single gRNA) Guide	$149	View Vector
Human WRNIP1 CRISPR adenovirus vector	Mammalian CRISPR Adenoviral Vector (Single gRNA) Guide	$299	View Vector

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