Vectors for Human XPC

Gene Information

  • Offical Gene Symbol XPC
  • Species Human (Homo sapiens)
  • Offical Full Name XPC complex subunit, DNA damage recognition and repair factor
  • Other Aliases RAD4; XP3; XPCC; p125
  • Other Desigations DNA repair protein complementing XP-C cells; mutant xeroderma pigmentosum group C; xeroderma pigmentosum, complementation group C
  • Gene Type protein-coding
  • Summary
    The protein encoded by this gene is a key component of the XPC complex, which plays an important role in the early steps of global genome nucleotide excision repair (NER). The encoded protein is important for damage sensing and DNA binding, and shows a preference for single-stranded DNA. Mutations in this gene or some other NER components can result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2017]
  • NCBI Gene ID 7508
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human XPC(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human XPC expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human XPC expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human XPC expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human XPC expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human XPC expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human XPC shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human XPC shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human XPC shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human XPC shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human XPC CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human XPC CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human XPC CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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