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Vectors for Microbat OAZ1

Gene Information

  • Offical Gene Symbol OAZ1
  • Species Microbat (Myotis lucifugus)
  • Offical Full Name -
  • Other Aliases -
  • Other Desigations ornithine decarboxylase antizyme 1
  • Gene Type protein-coding
  • Summary
    The protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamine in cells. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis pathway; thus, completing the auto-regulatory circuit. This gene encodes antizyme 1, the first member of the antizyme family, that has broad tissue distribution, and negatively regulates intracellular polyamine levels by binding to and targeting ODC for degradation, as well as by inhibiting polyamine uptake. Antizyme 1 mRNA contains two potential in-frame AUGs, and studies in rat suggest that alternative use of the two translation initiation sites results in N-terminally distinct protein isoforms with different subcellular localization (PMID:16120325). [provided by RefSeq, Jul 2014]
  • NCBI Gene ID 102431305
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | Ensembl |  UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Microbat OAZ1(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Microbat OAZ1 expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Microbat OAZ1 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Microbat OAZ1 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Microbat OAZ1 expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Microbat OAZ1 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189

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