Vectors for Microbat OAZ1

Gene Information

  • Offical Gene Symbol OAZ1
  • Species Microbat (Myotis lucifugus)
  • Offical Full Name -
  • Other Aliases -
  • Other Desigations ornithine decarboxylase antizyme 1
  • NCBI Gene ID 102431305
  • Summary
    The protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamine in cells. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis pathway; thus, completing the auto-regulatory circuit. This gene encodes antizyme 1, the first member of the antizyme family, that has broad tissue distribution, and negatively regulates intracellular polyamine levels by binding to and targeting ODC for degradation, as well as by inhibiting polyamine uptake. Antizyme 1 mRNA contains two potential in-frame AUGs, and studies in rat suggest that alternative use of the two translation initiation sites results in N-terminally distinct protein isoforms with different subcellular localization (PMID:16120325). [provided by RefSeq, Jul 2014]
  • NCBI  | Ensembl

Pre-Made Vectors for OAZ1 (These vectors are available immediately)

Gene Expression Vectors
These pre-made vectors are constructed with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
shRNA Knockdown Vectors
These pre-made vectors are constructed with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Name Vector Type Knockdown Score
{[ item.alias ]} {[ item.vector_type ]} {[ item.vector_type | boatFixI18nName: 'vectorSystem' | translate ]} {[ item.intrinsic_score ]}
View / Edit Vector 

Can’t find desired vectors above? Use options below to obtain custom vectors.

Design My Vector

Use this option to design your vector using our online platform.

You can request cloning & virus packaging services for your vector here.

Send Design Request

Use this option to ask our scientists to design your vector for free.

You can also submit other service inquires here, including:

  • Virus packaging
  • CRISPR targeting
  • BAC modification
  • Library construction
  • Plasmid DNA preparation
  • RNA preparation
  • Mutagenesis
  • and more...