Vectors for Microbat PEG10

Gene Information

  • Offical Gene Symbol PEG10
  • Species Microbat (Myotis lucifugus)
  • Offical Full Name -
  • Other Aliases -
  • Other Desigations retrotransposon-derived protein PEG10
  • Gene Type protein-coding
  • Summary
    This gene is thought to have been derived from the Ty3/Gypsy family of retrotransposons. It contains two overlapping open reading frames, RF1 and RF2, and expresses two proteins: a shorter, gag-like protein (with a CCHC-type zinc finger domain) from RF1; and a longer, gag/pol-like fusion protein (with an additional aspartic protease motif) from RF1/RF2 by -1 translational frameshifting (-1 FS). While -1 FS has been observed in RNA viruses and transposons in both prokaryotes and eukaryotes, this gene represents the first example of -1 FS in a eukaryotic cellular gene. This gene is highly conserved across mammalian species and retains the heptanucleotide (GGGAAAC) and pseudoknot elements required for -1 FS. It is expressed in adult and embryonic tissues (most notably in placenta) and reported to have a role in cell proliferation, differentiation, apoptosis and cancer development. Knockout mice lacking this gene showed early embryonic lethality with placental defects, indicating the importance of this gene in embryonic development. [provided by RefSeq, Oct 2014]
  • NCBI Gene ID 102436941
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI UCSC Genome Browser View

Popular Vector Designs for Microbat PEG10(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Microbat PEG10 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Microbat PEG10 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Microbat PEG10 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Microbat PEG10 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Microbat PEG10 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189

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