Mouse Chrne (Gene ID: 11448) vectors - Lentivirus, AAV, shRNA & CRISPR I VectorBuilder

Gene Information

Offical Gene Symbol Chrne
Species Mouse (Mus musculus)
Offical Full Name cholinergic receptor, nicotinic, epsilon polypeptide
Other Aliases AChrepsilon; Acre; nAChRE
Other Desigations acetylcholine receptor subunit epsilon; AchR epsilon subunit; nicotinic acetylcholine receptor epsilon subunit
Gene Type protein-coding
Summary
This gene encodes the epsilon subunit of the muscle-derived nicotinic acetylcholine receptor, a pentameric neurotransmitter receptor and member of the ligand-gated ion channel superfamily. The acetylcholine receptor changes subunit composition shortly after birth when the epsilon subunit replaces the gamma subunit seen in embryonic receptors. In mice, deficiency of this gene can lead to a decline in the number of nicotinic acetylcholine receptors at neuromuscular junctions and causes progressive muscle weakness, atrophy and premature death. Mutations in this gene serve as a pathophysiological model for human congenital myasthenia. Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Nov 2012]
NCBI Gene ID 11448
RefSeq Transcript
NM_009603.1
RefSeq Protein
NP_033733.1
External Links NCBI | Ensembl | UCSC Genome Browser View
View ORF sequence of this gene »

Vector Description	Vector Type	Price
Mouse Chrne expression regular plasmid vector	Mammalian Gene Expression Vector Guide	From $189
Mouse Chrne expression lentivirus vector	Mammalian Gene Expression Lentiviral Vector Guide	From $189
Mouse Chrne expression adenovirus vector	Mammalian Gene Expression Adenoviral Vector Guide	From $189
Mouse Chrne expression AAV vector	Mammalian Gene Expression AAV Vector Guide	From $189
Mouse Chrne expression PiggyBac vector	Mammalian Gene Expression PiggyBac Vector Guide	From $189

Vector Description	Vector Type	Price
Mouse Chrne shRNA lentivirus vector	Mammalian shRNA Knockdown Lentiviral Vector Guide	$149	View Vector
Mouse Chrne shRNA adenovirus vector	Mammalian shRNA Knockdown Adenoviral Vector Guide	$299	View Vector
Mouse Chrne shRNA AAV vector	Mammalian shRNA Knockdown AAV Vector Guide	$149	View Vector
Mouse Chrne shRNA PiggyBac vector	Mammalian shRNA Knockdown PiggyBac Vector Guide	$149	View Vector

Vector Description	Vector Type	Price
Mouse Chrne CRISPR regular plasmid vector	Mammalian CRISPR Vector (Single gRNA) Guide	$149	View Vector
Mouse Chrne CRISPR lentivirus vector	Mammalian CRISPR Lentiviral Vector (Single gRNA) Guide	$149	View Vector
Mouse Chrne CRISPR adenovirus vector	Mammalian CRISPR Adenoviral Vector (Single gRNA) Guide	$299	View Vector

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