Vectors for Mouse Gdf15

Gene Information

  • Offical Gene Symbol Gdf15
  • Species Mouse (Mus musculus)
  • Offical Full Name growth differentiation factor 15
  • Other Aliases MIC-1; NAG-1; SBF
  • Other Desigations growth/differentiation factor 15; macrophage inhibiting cytokine-1; macrophage inhibitory cytokine 1
  • Gene Type protein-coding
  • Summary
    This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The protein is expressed in a broad range of cell types, acts as a pleiotropic cytokine and is involved in the stress response program of cells after cellular injury. Increased protein levels are associated with disease states such as tissue hypoxia, inflammation, acute injury and oxidative stress. Mice lacking a functional copy of this gene exhibit progressive loss of motor neurons, and more rapid blood clot formation. [provided by RefSeq, Aug 2016]
  • NCBI Gene ID 23886
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | EnsemblUCSC Genome Browser View

Popular Vector Designs for Mouse Gdf15(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Gdf15 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $159
Mouse Gdf15 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $159
Mouse Gdf15 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $159
Mouse Gdf15 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $159
Mouse Gdf15 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $159
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Gdf15 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $99
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Mouse Gdf15 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $269
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Mouse Gdf15 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $99
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Mouse Gdf15 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $99
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Gdf15 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $99
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Mouse Gdf15 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $99
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Mouse Gdf15 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $269
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