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Vectors for Mouse Ikbkb

Gene Information

  • Offical Gene Symbol Ikbkb
  • Species Mouse (Mus musculus)
  • Offical Full Name inhibitor of kappaB kinase beta
  • Other Aliases IKK-2; IKK-B; IKK-beta; IKK2; IKK[b]; IKKbeta; NFKBIKB
  • Other Desigations inhibitor of nuclear factor kappa-B kinase subunit beta; I-kappa-B kinase 2; I-kappa-B-kinase beta; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta; nuclear factor NF-kappa-B inhibitor kinase beta; serine/threonine protein kinase IKBKB
  • Gene Type protein-coding
  • Summary
    Enables IkappaB kinase activity and protein phosphatase binding activity. Involved in peptidyl-serine phosphorylation and tumor necrosis factor-mediated signaling pathway. Acts upstream of or within B cell homeostasis; positive regulation of cation channel activity; and positive regulation of sodium ion transport. Located in cytoplasmic side of plasma membrane. Part of CD40 receptor complex. Is expressed in several structures, including genitourinary system and musculature. Used to study immunodeficiency 15A. Human ortholog(s) of this gene implicated in breast cancer; combined immunodeficiency (multiple); dermatitis; prostate cancer (multiple); and type 2 diabetes mellitus. Orthologous to human IKBKB (inhibitor of nuclear factor kappa B kinase subunit beta). [provided by Alliance of Genome Resources, Apr 2022]
  • NCBI Gene ID 16150
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | EnsemblUCSC Genome Browser View

Popular Vector Designs for Mouse Ikbkb(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Ikbkb expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Mouse Ikbkb expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Mouse Ikbkb expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Mouse Ikbkb expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Mouse Ikbkb expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Ikbkb shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Mouse Ikbkb shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Mouse Ikbkb shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Mouse Ikbkb shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Ikbkb CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Mouse Ikbkb CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Mouse Ikbkb CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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