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Vectors for Mouse Smurf1

Gene Information

  • Offical Gene Symbol Smurf1
  • Species Mouse (Mus musculus)
  • Offical Full Name SMAD specific E3 ubiquitin protein ligase 1
  • Other Aliases 4930431E10Rik; mKIAA1625
  • Other Desigations E3 ubiquitin-protein ligase SMURF1; HECT-type E3 ubiquitin transferase SMURF1; Smad ubiquitination regulatory factor 1
  • Gene Type protein-coding
  • Summary
    Predicted to enable I-SMAD binding activity; R-SMAD binding activity; and ubiquitin protein ligase activity. Involved in parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization. Acts upstream of or within negative regulation of ossification and protein ubiquitination. Predicted to be located in axon; neuronal cell body; and plasma membrane. Predicted to be active in cytoplasm. Predicted to colocalize with mitochondrion. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; genitourinary system; and respiratory system. Orthologous to human SMURF1 (SMAD specific E3 ubiquitin protein ligase 1). [provided by Alliance of Genome Resources, Apr 2022]
  • NCBI Gene ID 75788
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | EnsemblUCSC Genome Browser View

Popular Vector Designs for Mouse Smurf1(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Smurf1 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Mouse Smurf1 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Mouse Smurf1 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Mouse Smurf1 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Mouse Smurf1 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Smurf1 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Mouse Smurf1 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Mouse Smurf1 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Mouse Smurf1 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Smurf1 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Mouse Smurf1 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Mouse Smurf1 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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