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Vectors for Mouse Sox10

Gene Information

  • Offical Gene Symbol Sox10
  • Species Mouse (Mus musculus)
  • Offical Full Name SRY (sex determining region Y)-box 10
  • Other Aliases Dom; Sox21; gt
  • Other Desigations transcription factor SOX-10; SRY-box containing gene 10; dominant megacolon; transcription factor SOX-M
  • Gene Type protein-coding
  • Summary
    Enables DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in several processes, including negative regulation of canonical Wnt signaling pathway; neural crest cell migration; and neurogenesis. Acts upstream of or within several processes, including lacrimal gland development; melanocyte differentiation; and nervous system development. Located in cytoplasm and nucleus. Is extrinsic component of mitochondrial outer membrane. Is expressed in several structures, including alimentary system; genitourinary system; inner ear; mesenchyme derived from neural crest; and nervous system. Used to study Kallmann syndrome; PCWH syndrome; and Waardenburg syndrome type 4C. Human ortholog(s) of this gene implicated in Kallmann syndrome; PCWH syndrome; Waardenburg syndrome type 2E; and Waardenburg syndrome type 4C. Orthologous to human SOX10 (SRY-box transcription factor 10). [provided by Alliance of Genome Resources, Apr 2022]
  • NCBI Gene ID 20665
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | Ensembl |  UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Mouse Sox10(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Sox10 expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Mouse Sox10 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Mouse Sox10 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Mouse Sox10 expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Mouse Sox10 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Sox10 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide 
$149
View Vector 
Mouse Sox10 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide 
$299
View Vector 
Mouse Sox10 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide 
$149
View Vector 
Mouse Sox10 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide 
$149
View Vector 
CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Sox10 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide 
$149
View Vector 
Mouse Sox10 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide 
$149
View Vector 
Mouse Sox10 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide 
$299
View Vector 

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