Vectors for Mouse Sppl2a

Gene Information

  • Offical Gene Symbol Sppl2a
  • Species Mouse (Mus musculus)
  • Offical Full Name signal peptide peptidase like 2A
  • Other Aliases 2010106G01Rik; C130089K23Rik
  • Other Desigations signal peptide peptidase-like 2A; IMP-3; SPP-like 2A protein; intramembrane protease 3; presenilin-like protein 2; protein SPPL2a
  • Gene Type protein-coding
  • Summary
    Predicted to enable aspartic endopeptidase activity, intramembrane cleaving and protein homodimerization activity. Predicted to be involved in membrane protein ectodomain proteolysis; membrane protein intracellular domain proteolysis; and regulation of immune response. Predicted to act upstream of or within proteolysis. Located in late endosome membrane and lysosomal membrane. Is expressed in genitourinary system; skeleton; and thymus primordium. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human SPPL2A (signal peptide peptidase like 2A). [provided by Alliance of Genome Resources, Apr 2022]
  • NCBI Gene ID 66552
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | EnsemblUCSC Genome Browser View

Popular Vector Designs for Mouse Sppl2a(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Sppl2a expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Mouse Sppl2a expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Mouse Sppl2a expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Mouse Sppl2a expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Mouse Sppl2a expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Sppl2a shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Mouse Sppl2a shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Mouse Sppl2a shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Mouse Sppl2a shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Sppl2a CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Mouse Sppl2a CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Mouse Sppl2a CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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