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Vectors for Mouse Stat5b

Gene Information

  • Offical Gene Symbol Stat5b
  • Species Mouse (Mus musculus)
  • Offical Full Name signal transducer and activator of transcription 5B
  • Other Aliases -
  • Other Desigations signal transducer and activator of transcription 5B; mammary gland factor STAT5B
  • Gene Type protein-coding
  • Summary
    Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and protein dimerization activity. Involved in cellular response to growth factor stimulus; growth hormone receptor signaling pathway via JAK-STAT; and positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including animal organ development; positive regulation of defense response; and positive regulation of lymphocyte activation. Located in cytoplasm and nucleus. Is expressed in several structures, including brain; genitourinary system; gut; hemolymphoid system gland; and liver and biliary system. Human ortholog(s) of this gene implicated in growth hormone insensitivity syndrome with immune dysregulation 1 and growth hormone insensitivity syndrome with immune dysregulation 2. Orthologous to human STAT5B (signal transducer and activator of transcription 5B). [provided by Alliance of Genome Resources, Apr 2022]
  • NCBI Gene ID 20851
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | EnsemblUCSC Genome Browser View

Popular Vector Designs for Mouse Stat5b(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Stat5b expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Mouse Stat5b expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Mouse Stat5b expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Mouse Stat5b expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Mouse Stat5b expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Stat5b shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Mouse Stat5b shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Mouse Stat5b shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Mouse Stat5b shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Stat5b CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Mouse Stat5b CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Mouse Stat5b CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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