Vectors for Mouse Xiap

Gene Information

  • Offical Gene Symbol Xiap
  • Species Mouse (Mus musculus)
  • Offical Full Name X-linked inhibitor of apoptosis
  • Other Aliases 1110015C02Rik; Aipa; Api3; Birc4; IAP3; ILP-1; MIHA
  • Other Desigations E3 ubiquitin-protein ligase XIAP; IAP homolog A; RING-type E3 ubiquitin transferase XIAP; X-linked IAP; baculoviral IAP repeat-containing protein 4; inhibitor of apoptosis protein 3
  • Gene Type protein-coding
  • Summary
    The protein encoded by this gene is a member of the inhibitor of apoptosis (IAP) family of proteins. While first identified for its role in blocking apoptosis, this protein modulates many other signaling processes including nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kB) pathways and inflammatory responses. This protein blocks apoptosis by binding and inhibiting target caspases after they have been activated. Binding occurs to some, but not all, caspases. This protein has several conserved regions, including baculoviral IAP repeat (BIR) motifs and a RING finger E3 ligase domain. In humans, mutations in this gene are linked to immunodeficiency in X-linked lymphoproliferative syndrome type-2 (XLP-2). A pseudogene of this gene is found on chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014]
  • NCBI Gene ID 11798
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | EnsemblUCSC Genome Browser View

Popular Vector Designs for Mouse Xiap(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Xiap expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Mouse Xiap expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Mouse Xiap expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Mouse Xiap expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Mouse Xiap expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Xiap shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Mouse Xiap shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Mouse Xiap shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Mouse Xiap shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Xiap CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Mouse Xiap CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Mouse Xiap CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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