Vectors for Pig OAZ1

Gene Information

  • Offical Gene Symbol OAZ1
  • Species Pig (Sus scrofa)
  • Offical Full Name -
  • Other Aliases AZ1
  • Other Desigations ornithine decarboxylase antizyme 1; ornithine decarboxylase antizyme 1 short isoform
  • Summary
    The protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamine in cells. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis pathway; thus, completing the auto-regulatory circuit. This gene encodes antizyme 1, the first member of the antizyme family, that has broad tissue distribution, and negatively regulates intracellular polyamine levels by binding to and targeting ODC for degradation, as well as by inhibiting polyamine uptake. Antizyme 1 mRNA contains two potential in-frame AUGs, and studies in rat suggest that alternative use of the two translation initiation sites results in N-terminally distinct protein isoforms with different subcellular localization (PMID:16120325). Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Jul 2014]
  • NCBI Gene ID 397034
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | Ensembl

Popular Vector Designs for Pig OAZ1(These vectors can be made quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Pig OAZ1 expression regular plasmid vector Mammalian Gene Expression Vector EGFP/Puro From $159
Pig OAZ1 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector EGFP:T2A:Puro From $159
Pig OAZ1 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector EGFP From $159
Pig OAZ1 expression AAV vector Mammalian Gene Expression AAV Vector EGFP From $159
Pig OAZ1 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector EGFP/Puro From $159

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