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Vectors for Rat Adam17

Gene Information

  • Offical Gene Symbol Adam17
  • Species Rat (Rattus norvegicus)
  • Offical Full Name ADAM metallopeptidase domain 17
  • Other Aliases TACE
  • Other Desigations disintegrin and metalloproteinase domain-containing protein 17; ADAM 17; TNF-alpha convertase; TNF-alpha-converting enzyme; a disintegrin and metallopeptidase domain 17; a disintegrin and metalloprotease domain 17; a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme)
  • Gene Type protein-coding
  • Summary
    Predicted to enable PDZ domain binding activity; metalloendopeptidase activity involved in amyloid precursor protein catabolic process; and signaling receptor binding activity. Involved in several processes, including regulation of apoptotic process; regulation of signal transduction; and response to antineoplastic agent. Located in several cellular components, including apical part of cell; cell surface; and cytoplasmic vesicle. Biomarker of Alzheimer\'s disease; congestive heart failure; and thoracic aortic aneurysm. Human ortholog(s) of this gene implicated in Alzheimer\'s disease; inflammatory bowel disease; and type 2 diabetes mellitus. Orthologous to human ADAM17 (ADAM metallopeptidase domain 17). [provided by Alliance of Genome Resources, Apr 2022]
  • NCBI Gene ID 57027
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | Ensembl |  UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Rat Adam17(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Rat Adam17 expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Rat Adam17 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Rat Adam17 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Rat Adam17 expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Rat Adam17 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Rat Adam17 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide 
$149
View Vector 
Rat Adam17 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide 
$299
View Vector 
Rat Adam17 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide 
$149
View Vector 
Rat Adam17 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide 
$149
View Vector 
CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Rat Adam17 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide 
$149
View Vector 
Rat Adam17 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide 
$149
View Vector 
Rat Adam17 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide 
$299
View Vector 

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