Vectors for Zebra finch OAZ2

Gene Information

  • Offical Gene Symbol OAZ2
  • Species Zebra finch (Taeniopygia guttata)
  • Offical Full Name -
  • Other Aliases -
  • Other Desigations ornithine decarboxylase antizyme 2
  • Gene Type protein-coding
  • Summary
    The protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamine in cells. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis pathway; thus, completing the auto-regulatory circuit. This gene encodes antizyme 2, the second member of the antizyme family. Like antizyme 1, antizyme 2 has broad tissue distribution, inhibits ODC activity and polyamine uptake, and stimulates ODC degradation in vivo, however, it fails to promote ODC degradation in vitro. Antizyme 2 is expressed at lower levels than antizyme 1, but is evolutionary more conserved, suggesting it likely has an important biological role. Studies also show different subcellular localization of antizymes 1 and 2, indicating specific function for each antizyme in discrete compartments of the cell. [provided by RefSeq, Aug 2014] Annotation information: Annotation category: partial on reference assembly
  • NCBI Gene ID 100224503
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | EnsemblUCSC Genome Browser View

Popular Vector Designs for Zebra finch OAZ2(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Zebra finch OAZ2 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Zebra finch OAZ2 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Zebra finch OAZ2 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Zebra finch OAZ2 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Zebra finch OAZ2 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189

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