Vector Academy

Vector Academy is our knowledge base that serves as your resource for diving deeper into all things cloning, viruses, and gene delivery. We’re excited to share our expertise and what we’ve learned from decades of collective experience with you.

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Gene Delivery in the Spotlight | Jul 11, 2024

Unleashing the Power of Oncolytic Viruses: Design Strategies for Maximum Efficacy

Keywords: Oncolytic virus, tumor targeting, immune stimulation

A deep dive into the attributes and design of recombinant viruses for use as potent oncolytic agents in the clinic and why HSV and VACV are ideal oncolytic virus candidates.

Gene Delivery in the Spotlight | Oct 11, 2023

Driving CAR-T Therapy in the Clinic and with CRISPR

Keywords: CAR-T cell therapy, Kymriah CAR-T, immunotherpy

A deep dive into the biology behind CAR-T vectors, their clinical applications, and how CRISPR/Cas9 is being used to create the next generation of CAR therapeutics.

Gene Delivery in the Spotlight | Aug 16, 2023

Unveiling the Versatility of Vesicular Stomatitis Virus: Pseudotyping and Beyond

Keywords: VSV immunotherapy, oncolytic virus, pseudotyping

Vesicular stomatitis virus (VSV), known for its simplicity and well-explored biology, serves as an invaluable model in virology, particularly through pseudotyping, where its envelope protein is swapped with that of another virus.

Gene Delivery in the Spotlight | Aug 02, 2023

So Many Viral Options. How Do You Choose?

Keywords: Viral gene therapy, retrovirus, transient transfection

A comprehensive guide to selecting the appropriate viral vector for gene delivery experiments. The article examines how factors such as cell type, expression type, and insert size can impact your experiment while comparing the integration capabilities, carrying capacities, and tropisms of different viruses.