Vector Academy

Vector Academy is our knowledge base that serves as your resource for diving deeper into all things cloning, viruses, and gene delivery. We’re excited to share our expertise and what we’ve learned from decades of collective experience with you.

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Lessons in Gene Delivery | Sep 30, 2025

CRISPR Library Screening Made Simple | Part 1: Setting Up for Success

Keywords: CRISPR screening, gRNA library design, in vitro and in vivo models, library preparation

Explore the critical steps in designing and performing CRISPR screens and learn what to consider to set your screening project up for success.

Lessons in Gene Delivery | May 27, 2025

Gene Delivery Seminar Series: Modeling Neurodegenerative Disease Risk Using Induced Pluripotent Stem Cells

Keywords: Gene delivery seminar series, iPSCs, neurodegenerative disease, CRISPR

Dr. Narayan's innovative work shows how patient-derived iPSC models are transforming our understanding of AD while paving the way toward targeted therapies.

Gene Delivery in the Spotlight | Mar 21, 2025

Optimizing CRISPR: Technology and Approaches for High Efficiency Gene Editing

Keywords: CRISPR-Cas9, genome editing, CRISPR vector design, gene knockout, gene regulation

An overview of CRISPR-Cas9 tools and mechanisms, with practical tips to optimize vector design for efficient genome editing.

Lessons in Gene Delivery | Feb 10, 2025

CRISPR This Way: Choosing Between Delivery Systems

Keywords: CRISPR delivery, plasmid, virus, mRNA, RNP

A comparison of delivery systems to help you choose the optimal method for your CRISPR experiments, from research applications to clinical use.

Gene Delivery in the Spotlight | Oct 11, 2023

Driving CAR-T Therapy in the Clinic and with CRISPR

Keywords: CAR-T cell therapy, Kymriah CAR-T, immunotherpy

A deep dive into the biology behind CAR-T vectors, their clinical applications, and how CRISPR/Cas9 is being used to create the next generation of CAR therapeutics.

Troubleshooting Guides | Jul 10, 2023

Slipping Under Titer: Why Is My Viral Titer So Low?

Keywords: Viral titer, gene toxicity

If your viral titration is low, it could be because of titration method, improper vector or experimental design, or expression of toxic genes. Here we discuss troubleshooting all of these and more.

Gene Delivery in the Spotlight | Apr 24, 2023

GLAd to Be Treating DMD

Keywords: Muscular dystrophy, gutless adenovirus, gene therapy

Learn about exciting gene therapy approaches utilizing AAV, adenovirus and gutless adenovirus for treating Duchenne muscular dystrophy.