Abtibody Constant Region

VectorBuilder offers many popular vector components that users can choose from when designing their vectors. The tables below provide detailed information on these popular components, which are listed separately by category.
Heavy Chain Constant Region (CH)
Name Description Application Notes References Sequence
hlgG1-CH Human IgG1 heavy chain constant region Encodes the constant region of the human IgG1 heavy chain. Nucleic Acids Res. 10:4071 (1982); J Virol. 93:e02270 (2019); View
mlgG1-CH Mouse IgG1 heavy chain constant region Encodes the constant region of the mouse IgG1 heavy chain. Proc Natl Acad Sci U S A. 1980 Apr; 77(4): 2143–2147. View
mlgG2a-CH Mouse IgG2a heavy chain constant region Encodes the constant region of the mouse IgG2a heavy chain. Proc Natl Acad Sci U S A. 78: 4495 (1981) View
mlgG2b-CH Mouse IgG2b heavy chain constant region Encodes the constant region of the mouse IgG2b heavy chain. Proc Natl Acad Sci U S A. 78: 4495 (1981) View
Light Chain Constant Region (CL)
Name Description Application Notes References Sequence
hIgκ-CL Human immunoglobulin kappa light chain constant region Encodes the constant region of the human kappa light chain. Cell. 22(1 Pt 1):197 (1980); Appl Microbiol Biotechnol. 102:5953 (2018); J Virol. 93: e02270 (2019) View
hIgλ2-CL Human immunoglobulin lambda 2 light chain constant region Encodes the constant region of the human lambda 2 light chain. Immunogenetics. 25:63 (1987); J Immunol. 169:271 (2002); Acta Pharm Sin B. 9:960 (2019) View
mIgκ-CL Mouse immunoglobulin kappa light chain constant region Encodes the constant region of the mouse kappa light chain. Cell. 22(1 Pt 1):197 (1980); Curr Biol. 25:R820 (2015) View
mIgλ1-CL Mouse immunoglobulin lambda 1 light chain constant region Encodes the constant region of the mouse lambda 1 light chain. Nature. 298:380 (1982) View
mIgλ2-CL Mouse immunoglobulin lambda 2 light chain constant region Encodes the constant region of the mouse lambda 2 light chain. Nucleic Acids Res. 10:3831 (1982) View
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