Powerful Directed Evolution Platform for Novel AAV Vector Discovery
AAV is a highly popular gene delivery vector for a wide range of gene therapy and vaccine applications. However, several problems with existing AAV serotypes limit their therapeutic potential. To overcome existing AAV’s limitations, capsid engineering by directed evolution has been a critical area of research that has significantly accelerated the development of novel AAV variants with improved features. VectorBuilder’s capsid evolution platform expedites the discovery of novel AAV capsids with better performance of physiologically or clinically relevant properties.
Designing and Editing Vectors
