Vectors for Human ACLY

Gene Information

  • Offical Gene Symbol ACLY
  • Species Human ( Homo sapiens )
  • Offical Full Name ATP citrate lyase
  • Other Aliases ACL; ATPCL; CLATP
  • Other Desigations ATP-citrate synthase; ATP-citrate (pro-S-)-lyase; citrate cleavage enzyme
  • Gene Type protein-coding
  • Summary
    ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Dec 2014]
  • NCBI Gene ID 47
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNC

Popular Vector Designs for Human ACLY(These vectors can be made quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ACLY expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $159
Human ACLY expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $159
Human ACLY expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $159
Human ACLY expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $159
Human ACLY expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $159
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ACLY shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $99
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Human ACLY shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $99
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Human ACLY shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $99
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Human ACLY shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $99
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ACLY CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $99
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Human ACLY CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   $99
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Human ACLY CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   $239
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