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Vector Academy
Vector Academy is our knowledge base that serves as your resource for diving deeper into all things cloning, viruses, and gene delivery. We’re excited to share our expertise and what we’ve learned from decades of collective experience with you.
CRISPR Library Screening Made Simple | Part 1: Setting Up for Success
Keywords: CRISPR screening, gRNA library design, in vitro and in vivo models, library preparation
Explore the critical steps in designing and performing CRISPR screens and learn what to consider to set your screening project up for success.
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Enhancing mRNA Therapeutics in Two Shakes of a Poly(A) Tail
Keywords: mRNA vaccine, polyadenylation, poly(A) tail, mRNA stability
Learn about the crucial role of poly(A) tails in the life cycle of mRNAs and how to leverage this for optimal efficacy of mRNA-based therapeutics.
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Gene Delivery Seminar Series: Modeling Neurodegenerative Disease Risk Using Induced Pluripotent Stem Cells
Keywords: Gene delivery seminar series, iPSCs, neurodegenerative disease, CRISPR
Dr. Narayan's innovative work shows how patient-derived iPSC models are transforming our understanding of AD while paving the way toward targeted therapies.
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Optimizing CRISPR: Technology and Approaches for High Efficiency Gene Editing
Keywords: CRISPR-Cas9, genome editing, CRISPR vector design, gene knockout, gene regulation
An overview of CRISPR-Cas9 tools and mechanisms, with practical tips to optimize vector design for efficient genome editing.
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CRISPR This Way: Choosing Between Delivery Systems
Keywords: CRISPR delivery, plasmid, virus, mRNA, RNP
A comparison of delivery systems to help you choose the optimal method for your CRISPR experiments, from research applications to clinical use.
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Design Pitfall: Using The Same Promoter To Drive Two Genes In Lentiviral Vector
Keywords: Lentivirus, Vector Design, Repetitive Sequences
Using two identical promoters in a lentiviral vector causes detrimental effects on proper expression of the two open reading frames.
Read More ››Below you can view posts divided into introductory, experienced, and expert levels.
Lessons in Gene Delivery
An introduction to concepts and tools in gene delivery from mRNA and proteins to plasmids and viruses.
Gene Delivery in the Spotlight
From the news desk to VectorBuilder's labs, we highlight what is new and exciting in the field of gene delivery.
Troubleshooting Guides
A collection of tips and hypotheses based on the experience of the experts here at VectorBuilder.