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Tools

shRNA and CRISPR Design

shRNA Target Design

Design optimal shRNA sequences by knockdown score and position for your target sequence.

Sequence Analysis

Sequence Alignment

Pair-wise comparison of DNA, protein, or translation-based DNA sequences.

Sequence Dot Plot

Two-dimensional plot for identifying regions with similar features between two DNA or RNA sequences.

GC Content Calculator

Calculate GC content of entire sequence and specific regions.

DNA Secondary Structure

Predict secondary structures from base pair interactions.

DNA Reverse Complement

Retrieve reverse, complement, or reverse complement sequences.

Sequence Optimization Analysis

Codon Optimization

Optimize codons according to species, cleavage sites, and clonability.

DNA Translation

Retrieve amino acid sequence from DNA input.