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For several years we have used VectorBuilder for generating expression constructs and custom AAVs. Designing constructs is easy – either use the website or send a request of what you want by email - detailed construct designs are usually in your inbox within 24 hrs. Prices, turnaround times and quality of product mean that ordering from VectorBuilder is just the obvious decision to make when planning experiments. I recommend their services to all my friends.
Rich selection of epitope-tags and promoters help you quick design custom vectors. I no longer waste my time to look into such information. VectorBuilder's design portal is convenient and useful.
Vectorbuilder's service is extremely consistent. We started with regular plasmids and AAV plasmids. Since last year we have ordered many piggybac plasmids. All worked as expected.
We have successfully generated several vectors with VectorBuilder and very much hope there will be many more to come. Their website is very easy to navigate. Timing is really appealing and the prices are convenient. Special thanks to Shelley Wu, the service rep in San Diego. She is extremely helpful and approachable. Overall, VectorBuilder is a huge help!
The straightforward, intuitive interface allowed me to design my construct, by a simply copying-and-pasting sequence of my gene and choosing the right promoter and reporter from an impressive scroll down menu. The vector and recombinant viruses were made on time at a very competitive price with no extra cost for aliquoting into working aliquots. I highly recommend VectorBuilder for a complete recombinant virus production pipeline.
VectorBuilder has been the partner every researcher would wish for during those dark moments of paper revision. They offer the complete package: a wide range of viral vector design options, an extremely user-friendly and intuitive website, direct communication, personal and knowledgeable step-by-step guidance throughout the designing and ordering process, accountability, amazing discounts, unique customer support, fast shipping, and guaranteed virus titers and efficiency. So here’s my big thumbs up for a great product and service provider who has proven indispensable in addressing my research questions!
VectorBuilder has provided incredible value and customer service throughout the entire process from product selection, custom design assistance, order submission, status reports and ultimate delivery management. The custom products I purchased from them performed exactly as advertised and in fact surpassed my expectations. I would recommend VectorBuilder to anyone requiring this type of product.
It has been a great experience working with Vectorbuilder! Their assistance has helped me concentrate on answering biological questions rather than dealing with the hassle of cloning. Vectorbuilder's friendly representatives and timely delivery make the processes easy.
I readily recommend a Vector Builder. My company has used them to produce research great plasmids and AAV vectors. They are helpful and responsive and have always delivered on time and on budget.
We do frequent new vector design and creation for our products. I ordered several custom vectors from Vector Builder using their evolutional platform. That platform is easy to put my gene interested and indicator. They synthesis, sequencing my genes to verify their sequence no mistake and make plasmid for me. Everything is wonderful. More important is the vector expression at high level to meet my requirement. I really recommend to use Vector Builder as your vector designing and creating candidate.
The services provided by VectorBuilder are excellent. I had a few vector constructs made by the VectorBuilder. The description of the constructs by their software is excellent. The technical team of the company seems to have a sound knowledge and the technical suggestion regarding vector construction given to me by them were excellent.
I ordered the cloning of a large gene (about 6 kbp) to the plasmid. VectorBuilder provided the construct with a correct sequence at a reasonable price. So I strongly recommend VectorBuilder's services for cloning of large genes.
NLRP3 inflammasome activation through heart-brain interaction initiates cardiac inflammation and hypertrophy during pressure overload
Stromal changes in the aged lung induce an emergence from melanoma dormancy
Lung-selective mRNA delivery of synthetic lipid nanoparticles for the treatment of pulmonary lymphangioleiomyomatosis
Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis
Modulation of the HIF2α-NCOA4 axis in enterocytes attenuates iron loading in a mouse model of hemochromatosis
Mitochondrial cristae-remodeling protein OPA1 in POMC neurons couples Ca2+ homeostasis with adipose tissue lipolysis
Prenatal interleukin 6 elevation increases glutamatergic synapse density and disrupts hippocampal connectivity in offspring
PI (3, 4) P2-mediated cytokinetic abscission prevents early senescence and cataract formation
Paired box 6 programs essential exocytotic genes in the regulation of glucose-stimulated insulin secretion and glucose homeostasis
Endogenous Retroviral Elements Generate Pathologic Neutrophils in Pulmonary Arterial Hypertension
YAP/TAZ drives cell proliferation and tumour growth via a polyamine–eIF5A hypusination–LSD1 axis
Hypothalamic dopamine signaling regulates brown fat thermogenesis
MARK4 controls ischaemic heart failure through microtubule detyrosination
Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex
Lactic acid promotes PD-1 expression in regulatory T cells in highly glycolytic tumor microenvironments
Convergent somatic mutations in metabolism genes in chronic liver disease
A Single-Cell Transcriptomics CRISPR-Activation Screen Identifies Epigenetic Regulators of the Zygotic Genome Activation Program
Reprogramming roadmap reveals route to human induced trophoblast stem cells
A simple and rapid method for enzymatic synthesis of CRISPR-Cas9 sgRNA libraries
A high-affinity human TCR-like antibody detects celiac disease gluten peptide-MHC complexes and inhibits T cell activation
snRNA-seq reveals a subpopulation of adipocytes that regulates thermogenesis
Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis
Transcriptional super-enhancers control cancer stemness and metastasis genes in squamous cell carcinoma
A bivalent vaccine containing D614G and BA.1 spike trimer proteins or a BA.1 spike trimer protein booster shows broad neutralizing immunity
Identification of natural compounds as SARS-CoV-2 entry inhibitors by molecular docking-based virtual screening with bio-layer interferometry
The resolvin D1 receptor GPR32 transduces inflammation resolution and atheroprotection
Indomethacin-induced oxidative stress enhances death receptor 5 signaling and sensitizes tumor cells to adoptive T-cell therapy