Vectors for Human ACTN1

Gene Information

  • Offical Gene Symbol ACTN1
  • Species Human ( Homo sapiens )
  • Offical Full Name actinin alpha 1
  • Other Aliases BDPLT15
  • Other Desigations alpha-actinin-1; F-actin cross-linking protein; actinin 1 smooth muscle; alpha-actinin cytoskeletal isoform; epididymis secretory sperm binding protein; non-muscle alpha-actinin-1
  • Gene Type protein-coding
  • Summary
    Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • NCBI Gene ID 87
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNC

Popular Vector Designs for Human ACTN1(These vectors can be made quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ACTN1 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  EGFP/Puro From $159
Human ACTN1 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  EGFP:T2A:Puro From $159
Human ACTN1 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  EGFP From $159
Human ACTN1 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  EGFP From $159
Human ACTN1 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  EGFP/Puro From $159
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ACTN1 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  EGFP:T2A:Puro $99
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Human ACTN1 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  EGFP $99
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Human ACTN1 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  EGFP $99
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Human ACTN1 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  EGFP:T2A:Puro $99
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ACTN1 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  EGFP/Puro $99
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Human ACTN1 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Puro $99
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Human ACTN1 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   EGFP $239
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Pre-Made Vectors for Human ACTN1 (These vectors are in stock and available immediately)

shRNA Knockdown Vectors
These pre-made vectors are constructed with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Name Vector Type Knockdown Score
Knockdown scores estimate the efficiency and specificity of shRNAs in knocking down target genes. Scores are calculated from a set of rules, and mostly range from 0 (worst) to 15 (best).
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Marker Price
pLV[shRNA]-mCherry:T2A:Puro-U6>hACTN1[shRNA#1] Mammalian shRNA Knockdown Lentiviral Vector   Guide  15.0 mCherry:T2A:Puro $99 View Vector 
pLV[shRNA]-mCherry:T2A:Puro-U6>hACTN1[shRNA#2] Mammalian shRNA Knockdown Lentiviral Vector   Guide  13.2 mCherry:T2A:Puro $99 View Vector 
pLV[shRNA]-mCherry:T2A:Puro-U6>hACTN1[shRNA#3] Mammalian shRNA Knockdown Lentiviral Vector   Guide  13.2 mCherry:T2A:Puro $99 View Vector 

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