Vectors for Human ADAMTS2

Gene Information

  • Offical Gene Symbol ADAMTS2
  • Species Human ( Homo sapiens )
  • Offical Full Name ADAM metallopeptidase with thrombospondin type 1 motif 2
  • Other Aliases ADAM-TS2; ADAMTS-2; ADAMTS-3; EDSDERMS; NPI; PC I-NP; PCI-NP; PCINP; PCPNI; PNPI
  • Other Desigations A disintegrin and metalloproteinase with thrombospondin motifs 2; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 2; procollagen I N-proteinase; procollagen I/II amino propeptide-processing enzyme; procollagen N-endopeptidase
  • Gene Type protein-coding
  • Summary
    This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature procollagen N-proteinase. This proteinase excises the N-propeptide of the fibrillar procollagens types I-III and type V. Mutations in this gene cause Ehlers-Danlos syndrome type VIIC, a recessively inherited connective-tissue disorder. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
  • NCBI Gene ID 9509
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNC

Popular Vector Designs for Human ADAMTS2(These vectors can be made quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ADAMTS2 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  EGFP/Puro From $159
Human ADAMTS2 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  EGFP:T2A:Puro From $159
Human ADAMTS2 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  EGFP From $159
Human ADAMTS2 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  EGFP From $159
Human ADAMTS2 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  EGFP/Puro From $159
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ADAMTS2 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  EGFP:T2A:Puro $99
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Human ADAMTS2 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  EGFP $99
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Human ADAMTS2 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  EGFP $99
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Human ADAMTS2 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  EGFP:T2A:Puro $99
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ADAMTS2 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  EGFP/Puro $99
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Human ADAMTS2 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Puro $99
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Human ADAMTS2 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   EGFP $239
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