Vectors for hM3D(Gq)

Gene Information

  • Gene Name hM3D(Gq)
  • Type ORF
  • Subtype Muscarinic Designer Receptor
  • Description A modified form of human Gq-coupled M3 muscarinic receptor, belonging to a class of chemogenetic receptors called designer receptors exclusively activated by designer drugs (DREADD)
  • Application Notes Allows engagement of the Gq signaling pathway in the presence of the synthetic ligand clozapine-N-oxide (CNO), leading to intracellular calcium ion release and enhanced neuronal excitation.
  • References Proc Natl Acad Sci U S A. 104:5163 (2007)
  • View ORF sequence of this gene »

Premade Vectors for hM3D(Gq) (These vectors are in stock and available immediately)

Gene Expression Vectors
These premade vectors are constructed with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
pAAV[Exp]-CMV>hM3D(Gq):oPRE Mammalian Gene Expression AAV Vector - $159.00 View Vector 
pPB[Exp]-Bsd-CBh>hM3D(Gq) Mammalian Gene Expression PiggyBac Vector Bsd $159.00 View Vector 

Popular Vector Designs for hM3D(Gq)(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
hM3D(Gq) expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $159
hM3D(Gq) expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $159
hM3D(Gq) expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $159
hM3D(Gq) expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $159
hM3D(Gq) expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $159

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