Vectors for hM4D(Gi)

Gene Information

  • Gene Name hM4D(Gi)
  • Type ORF
  • Subtype Muscarinic Designer Receptor
  • Description A modified form of human Gi-coupled M4 muscarinic receptor, belonging to a class of chemogenetic receptors called designer receptors exclusively activated by designer drugs (DREADD)
  • Application Notes Allows engagement of the Gi signaling pathway in the presence of the synthetic ligand clozapine-N-oxide (CNO), leading to potassium ion influx and decreased neuronal firing rates.
  • References Proc Natl Acad Sci U S A. 104:5163 (2007)
  • View ORF sequence of this gene »

Popular Vector Designs for hM4D(Gi)(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
hM4D(Gi) expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $159
hM4D(Gi) expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $159
hM4D(Gi) expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $159
hM4D(Gi) expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $159
hM4D(Gi) expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $159

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