Vectors for Human A2ML1

Gene Information

  • Offical Gene Symbol A2ML1
  • Species Human ( Homo sapiens )
  • Offical Full Name alpha-2-macroglobulin like 1
  • Other Aliases CPAMD9; OMS; p170
  • Other Desigations alpha-2-macroglobulin-like protein 1; C3 and PZP-like, alpha-2-macroglobulin domain containing 9
  • Gene Type protein-coding
  • Summary
    This gene encodes a member of the alpha-macroglobulin superfamily. The encoded protein is thought to be an N-glycosylated monomeric protein that acts as an inhibitor of several proteases. It has been shown to form covalent interactions with proteases, and has been reported as the p170 antigen recognized by autoantibodies in the autoimmune disease paraneoplastic pemphigus (PNP; PMID:20805888). Mutations in these gene have also been associated with some cases of Noonan syndrome (NS; PMID:24939586) as well as some cases of otitis media (PMID:26121085). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]
  • NCBI Gene ID 144568
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNC

Popular Vector Designs for Human A2ML1(These vectors can be made quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human A2ML1 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $159
Human A2ML1 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $159
Human A2ML1 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $159
Human A2ML1 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $159
Human A2ML1 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $159
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human A2ML1 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $99
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Human A2ML1 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $99
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Human A2ML1 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $99
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Human A2ML1 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $99
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human A2ML1 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $99
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Human A2ML1 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   $99
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Human A2ML1 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   $239
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