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Technical Bulletin

Interplay between SLIRP activity and exercise training sheds light on mitochondrial plasticity in skeletal muscle
Mitochondrial dysfunction has been linked to a reduction in muscle mass and strength observed in patients with conditions such as cancer, type 2 diabetes, and sarcopenia. Recently, a research group at the University of Copenhagen, led by Dr Tang Cam... Read More ››
Latest Discovery
Cannibalistic Cancer Cells Studied in High Definition
Chemotherapy is a commonly-used treatment for multiple forms of cancer. However, when cancer cells survive chemotherapy treatment, they can phagocytose, or “eat”, other cells for nutrients and energy. Recently, a team at the University of Tulane was... Read More ››
Latest Discovery
Protein involved in Alzheimer's disease tau neurotoxicity identified
Alzheimer's disease is the most common type of dementia and affects ~55 million people worldwide. Aggregation of tau is a defining feature of Alzheimer’s disease. Recently, researchers at the Indiana University School of Medicine identified Bassoon,... Read More ››
Interesting Story
Gene therapy rescues metabolic function in lipodystrophy
Gene therapy is emerging as a promising candidate to treat a wide range of metabolic disorders. Recently, Dr. George Mcilroy and his team at the University of Aberdeen Rowett Institute and Cardiovascular and Diabetes Centre demonstrated the efficacy... Read More ››
Research Trend
Novel oncogenic fusion discovered and classified in pheochromocytoma
Pheochromocytoma is a rare tumor that develops in the adrenal glands. To discover novel driver events of the disease, Dr. Patricia Dahia and her team at the University of Texas San Antonio Division of Hematology and Medical Oncology conducted whole... Read More ››
Interesting Story
Single dose of off-the-shelf gene therapy boosts the immune system to fight cancer
One of the major challenges in the clinic for the treatment of various diseases is the ability to consistently deliver therapeutics at efficacious levels. Recently, researchers in the Division of Hematology and Oncology at Nationwide Children’s Hos... Read More ››
Research Trend
Gold labeled antibody fragments provide insight into the senses
Stereocilia are important structures found in the inner ear that are involved in hearing and balance. Recently, scientists at the Vollum Institute at the Oregon Health and Science University were able to provide insight into the structure and confo... Read More ››
Interesting Story
Molecular barcodes offer insight into cancer
New advances in molecular barcoding offer exciting possibilities, especially in cancer research. Over the years, molecular barcoding involved generating specific nucleic acids or proteins within cells to trace lineages across generations to observe... Read More ››
Breaking News
SARS-CoV-2 variants: Human antibody-mediated immunity or Harry Houdini?
The pandemic COVID-19 has caused over 2 million deaths globally with the numbers increasing at an alarming rate. A monumental worldwide vaccination program is being rolled out with several companies including AstraZeneca/Oxford University, Pfizer/Bi... Read More ››
Latest Discovery
A real breakthrough for Parkinson’s disease?
One of the greatest barriers to treating neural degeneration and neural tissue injury is the fact that neurons do not proliferate, and there are only a few areas of the brain that exhibit neurogenesis. It is possible to convert one somatic cell type... Read More ››
Research Trend
A powerful mouse model for studying Covid-19
We have all been engulfed by the current SARS-CoV-2 pandemic with the lives of millions affected. To date, COVID-19 has resulted in almost 8 million confirmed cases with over 400,000 deaths. Considerable effort and money have been invested in trying... Read More ››
Breaking News
Coronavirus – How it began
During the beginning of this year, a novel coronavirus disease — termed Covid-19 by the WHO — was identified as being responsible for a sudden increase in cases of pneumonia in hospitalized patients. We have seen this rapidly escalate into a global... Read More ››
Latest Discovery
De-arming CRISPR/Cas9 to increase knock-in efficiency
The ability to knock in (KI) DNA sequences via homologous recombination (HR) to generate knockout (KO) mice was first demonstrated 30 years ago by Mario R. Capecchi, Martin J. Evans and Oliver Smithies (1,2). In recent years, CRISPR/Cas9 has revolut... Read More ››
Research Trend
A new scar reduction role for engineered T cells
Cardiovascular diseases (CVDs) are the number one cause of death globally, responsible for 31% of all human mortalities. This is in part due to lifestyle but also because the human heart is incapable of functional regeneration following injury or on... Read More ››
Interesting Story
The painless people
Wouldn’t it be nice if we felt no pain? Although lacking the ability to feel pain sounds tempting, considering we could have simply moved on with our lives without going through the hassle of tending to our injuries, the consequences of being painles... Read More ››
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