Vectors for Human ACTL6A

Gene Information

  • Offical Gene Symbol ACTL6A
  • Species Human ( Homo sapiens )
  • Offical Full Name actin like 6A
  • Other Aliases ACTL6; ARPN-BETA; Arp4; BAF53A; INO80K
  • Other Desigations actin-like protein 6A; 53 kDa BRG1-associated factor A; BAF complex 53 kDa subunit; BAF53; BRG1-associated factor 53A; INO80 complex subunit K; actin-related protein 4; actin-related protein Baf53a; arpNbeta; hArpN beta
  • Gene Type protein-coding
  • Summary
    This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described. [provided by RefSeq, Jul 2008]
  • NCBI Gene ID 86
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNC

Popular Vector Designs for Human ACTL6A(These vectors can be made quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ACTL6A expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $159
Human ACTL6A expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $159
Human ACTL6A expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $159
Human ACTL6A expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $159
Human ACTL6A expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $159
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ACTL6A shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $99
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Human ACTL6A shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $99
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Human ACTL6A shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $99
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Human ACTL6A shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $99
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ACTL6A CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $99
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Human ACTL6A CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   $99
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Human ACTL6A CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   $239
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