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Vectors for Human ATP6V1B1

Gene Information

  • Offical Gene Symbol ATP6V1B1
  • Species Human (Homo sapiens)
  • Offical Full Name ATPase H+ transporting V1 subunit B1
  • Other Aliases ATP6B1; DRTA2; RTA1B; VATB; VMA2; VPP3
  • Other Desigations V-type proton ATPase subunit B, kidney isoform; ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1; H(+)-transporting two-sector ATPase, 58kD subunit; H+-ATPase beta 1 subunit; V-ATPase B1 subunit; V-ATPase subunit B 1; endomembrane proton pump 58 kDa subunit; vacuolar proton pump 3; vacuolar proton pump subunit B 1; vacuolar proton pump, subunit 3
  • Gene Type protein-coding
  • Summary
    This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c\', c\'\', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain B subunit isoforms and is found in the kidney. Mutations in this gene cause distal renal tubular acidosis associated with sensorineural deafness. [provided by RefSeq, Jul 2008]
  • NCBI Gene ID 525
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNC |  UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Human ATP6V1B1(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ATP6V1B1 expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Human ATP6V1B1 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Human ATP6V1B1 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Human ATP6V1B1 expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Human ATP6V1B1 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ATP6V1B1 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide 
$149
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Human ATP6V1B1 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide 
$299
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Human ATP6V1B1 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide 
$149
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Human ATP6V1B1 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide 
$149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ATP6V1B1 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide 
$149
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Human ATP6V1B1 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide 
$149
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Human ATP6V1B1 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide 
$299
View Vector 

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