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Vectors for Human CACNA2D2

Gene Information

  • Offical Gene Symbol CACNA2D2
  • Species Human (Homo sapiens)
  • Offical Full Name calcium voltage-gated channel auxiliary subunit alpha2delta 2
  • Other Aliases CACNA2D; CASVDD
  • Other Desigations voltage-dependent calcium channel subunit alpha-2/delta-2; alpha 2 delta calcium channel subunit; alpha2delta-2; calcium channel, voltage-dependent, alpha 2/delta subunit 2; gene 26; voltage-gated calcium channel subunit alpha-2/delta-2
  • Gene Type protein-coding
  • Summary
    Calcium channels mediate the entry of calcium ions into the cell upon membrane polarization. This gene encodes the alpha-2/delta subunit of the voltage-dependent calcium channel complex. The complex consists of the main channel-forming subunit alpha-1, and auxiliary subunits alpha-2/delta, beta, and gamma. The auxiliary subunits function in the assembly and membrane localization of the complex, and modulate calcium currents and channel activation/inactivation kinetics. The subunit encoded by this gene undergoes post-translational cleavage to yield the extracellular alpha2 peptide and a membrane-anchored delta polypeptide. This subunit is a receptor for the antiepileptic drug, gabapentin. Mutations in this gene are associated with early infantile epileptic encephalopathy. Single nucleotide polymorphisms in this gene are correlated with increased sensitivity to opioid drugs. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014]
  • NCBI Gene ID 9254
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNC |  UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Human CACNA2D2(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human CACNA2D2 expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Human CACNA2D2 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Human CACNA2D2 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Human CACNA2D2 expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Human CACNA2D2 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human CACNA2D2 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide 
$149
View Vector 
Human CACNA2D2 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide 
$299
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Human CACNA2D2 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide 
$149
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Human CACNA2D2 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide 
$149
View Vector 
CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human CACNA2D2 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide 
$149
View Vector 
Human CACNA2D2 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide 
$149
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Human CACNA2D2 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide 
$299
View Vector 

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