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Vectors for Human CASP14

Gene Information

  • Offical Gene Symbol CASP14
  • Species Human (Homo sapiens)
  • Offical Full Name caspase 14
  • Other Aliases ARCI12; caspase-14
  • Other Desigations caspase-14; CASP-14; apoptosis-related cysteine protease; caspase 14, apoptosis-related cysteine peptidase; caspase 14, apoptosis-related cysteine protease; mini-ICE
  • Gene Type protein-coding
  • Summary
    This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier. [provided by RefSeq, Jul 2008]
  • NCBI Gene ID 23581
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human CASP14(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human CASP14 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human CASP14 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human CASP14 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human CASP14 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human CASP14 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human CASP14 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human CASP14 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human CASP14 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human CASP14 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human CASP14 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human CASP14 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human CASP14 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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