Vectors for Human CNMD

Gene Information

  • Offical Gene Symbol CNMD
  • Species Human (Homo sapiens)
  • Offical Full Name chondromodulin
  • Other Aliases BRICD3; CHM-I; CHM1; LECT1; MYETS1
  • Other Desigations leukocyte cell-derived chemotaxin 1; BRICHOS domain containing 3; chondromodulin-1; chondromodulin-I; leukocyte cell derived chemotaxin 1; multiple myeloma tumor suppressor 1
  • Gene Type protein-coding
  • Summary
    This gene encodes a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This gene is expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • NCBI Gene ID 11061
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human CNMD(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human CNMD expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $159
Human CNMD expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $159
Human CNMD expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $159
Human CNMD expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $159
Human CNMD expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $159
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human CNMD shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $99
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Human CNMD shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $269
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Human CNMD shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $99
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Human CNMD shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $99
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human CNMD CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $99
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Human CNMD CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $99
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Human CNMD CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $269
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