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Vectors for Human DHCR24

Gene Information

  • Offical Gene Symbol DHCR24
  • Species Human (Homo sapiens)
  • Offical Full Name 24-dehydrocholesterol reductase
  • Other Aliases DCE; Nbla03646; SELADIN1; seladin-1
  • Other Desigations delta(24)-sterol reductase; 3 beta-hydroxysterol delta 24-reductase; 3beta-hydroxysterol delta24 reductase; desmosterol-to-cholesterol enzyme; diminuto/dwarf1 homolog; seladin 1; selective AD indicator 1
  • Gene Type protein-coding
  • Summary
    This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells. [provided by RefSeq, Jul 2008]
  • NCBI Gene ID 1718
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNC |  UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Human DHCR24(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human DHCR24 expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Human DHCR24 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Human DHCR24 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Human DHCR24 expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Human DHCR24 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human DHCR24 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide 
$149
View Vector 
Human DHCR24 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide 
$299
View Vector 
Human DHCR24 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide 
$149
View Vector 
Human DHCR24 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide 
$149
View Vector 
CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human DHCR24 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide 
$149
View Vector 
Human DHCR24 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide 
$149
View Vector 
Human DHCR24 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide 
$299
View Vector 

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