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Vectors for Human DYNC2LI1

Gene Information

  • Offical Gene Symbol DYNC2LI1
  • Species Human (Homo sapiens)
  • Offical Full Name dynein cytoplasmic 2 light intermediate chain 1
  • Other Aliases CGI-60; D2LIC; LIC3
  • Other Desigations cytoplasmic dynein 2 light intermediate chain 1
  • Gene Type protein-coding
  • Summary
    This gene encodes a protein that is a component of the dynein-2 microtubule motor protein complex that plays a role in the retrograde transport of cargo in primary cilia via the intraflagellar transport system. This gene is ubiquitously expressed and its protein, which localizes to the axoneme and Golgi apparatus, interacts directly with the cytoplasmic dynein 2 heavy chain 1 protein to form part of the multi-protein dynein-2 complex. Mutations in this gene produce defects in the dynein-2 complex which result in several types of ciliopathy including short-rib thoracic dysplasia 15 with polydactyly (SRTD15). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2017]
  • NCBI Gene ID 51626
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNC |  UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Human DYNC2LI1(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human DYNC2LI1 expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Human DYNC2LI1 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Human DYNC2LI1 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Human DYNC2LI1 expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Human DYNC2LI1 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human DYNC2LI1 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide 
$149
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Human DYNC2LI1 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide 
$299
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Human DYNC2LI1 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide 
$149
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Human DYNC2LI1 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide 
$149
View Vector 
CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human DYNC2LI1 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide 
$149
View Vector 
Human DYNC2LI1 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide 
$149
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Human DYNC2LI1 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide 
$299
View Vector 

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