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Vectors for Human ERCC2

Gene Information

  • Offical Gene Symbol ERCC2
  • Species Human (Homo sapiens)
  • Offical Full Name ERCC excision repair 2, TFIIH core complex helicase subunit
  • Other Aliases COFS2; EM9; TFIIH; TTD; TTD1; XPD
  • Other Desigations general transcription and DNA repair factor IIH helicase subunit XPD; BTF2 p80; CXPD; DNA excision repair protein ERCC-2; DNA repair protein complementing XP-D cells; TFIIH 80 kDa subunit; TFIIH basal transcription factor complex 80 kDa subunit; TFIIH basal transcription factor complex helicase XPB subunit; TFIIH basal transcription factor complex helicase XPD subunit; TFIIH basal transcription factor complex helicase subunit; TFIIH p80; TFIIH subunit XPD; basic transcription factor 2 80 kDa subunit; excision repair cross-complementation group 2; excision repair cross-complementing rodent repair deficiency, complementation group 2; xeroderma pigmentosum complementary group D; xeroderma pigmentosum group D-complementing protein
  • Gene Type protein-coding
  • Summary
    The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
  • NCBI Gene ID 2068
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human ERCC2(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ERCC2 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human ERCC2 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human ERCC2 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human ERCC2 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human ERCC2 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ERCC2 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human ERCC2 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human ERCC2 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human ERCC2 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ERCC2 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human ERCC2 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human ERCC2 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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