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Vectors for Human ERCC5

Gene Information

  • Offical Gene Symbol ERCC5
  • Species Human (Homo sapiens)
  • Offical Full Name ERCC excision repair 5, endonuclease
  • Other Aliases COFS3; ERCC5-201; ERCM2; UVDR; XPG; XPGC
  • Other Desigations DNA excision repair protein ERCC-5; DNA repair protein complementing XP-G cells; XPG-complementing protein; excision repair cross-complementation group 5; excision repair cross-complementing rodent repair deficiency, complementation group 5; xeroderma pigmentosum, complementation group G
  • Gene Type protein-coding
  • Summary
    This gene encodes a single-strand specific DNA endonuclease that makes the 3\' incision in DNA excision repair following UV-induced damage. The protein may also function in other cellular processes, including RNA polymerase II transcription, and transcription-coupled DNA repair. Mutations in this gene cause xeroderma pigmentosum complementation group G (XP-G), which is also referred to as xeroderma pigmentosum VII (XP7), a skin disorder characterized by hypersensitivity to UV light and increased susceptibility for skin cancer development following UV exposure. Some patients also develop Cockayne syndrome, which is characterized by severe growth defects, cognitive disability, and cachexia. Read-through transcription exists between this gene and the neighboring upstream BIVM (basic, immunoglobulin-like variable motif containing) gene. [provided by RefSeq, Feb 2011]
  • NCBI Gene ID 2073
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNC |  UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Human ERCC5(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ERCC5 expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Human ERCC5 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Human ERCC5 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Human ERCC5 expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Human ERCC5 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ERCC5 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide 
$149
View Vector 
Human ERCC5 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide 
$299
View Vector 
Human ERCC5 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide 
$149
View Vector 
Human ERCC5 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide 
$149
View Vector 
CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ERCC5 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide 
$149
View Vector 
Human ERCC5 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide 
$149
View Vector 
Human ERCC5 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide 
$299
View Vector 

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