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Vectors for Human ERVFRD-1

Gene Information

  • Offical Gene Symbol ERVFRD-1
  • Species Human (Homo sapiens)
  • Offical Full Name endogenous retrovirus group FRD member 1, envelope
  • Other Aliases ERVFRDE1; GLLL6191; HERV-FRD; HERV-W/FRD; UNQ6191; envFRD
  • Other Desigations syncytin-2; HERV-FRD provirus ancestral Env polyprotein; HERV-FRD_6p24.1 provirus ancestral Env polyprotein; endogenous retrovirus group FRD, member 1; envelope polyprotein; syncytin 2
  • Gene Type protein-coding
  • Summary
    Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of a human endogenous retrovirus provirus on chromosome 6 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene\'s protein product plays a major role in placental development and trophoblast fusion. The protein has the characteristics of a typical retroviral envelope protein, including a cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer. [provided by RefSeq, Jun 2012]
  • NCBI Gene ID 405754
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human ERVFRD-1(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ERVFRD-1 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human ERVFRD-1 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human ERVFRD-1 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human ERVFRD-1 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human ERVFRD-1 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ERVFRD-1 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human ERVFRD-1 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human ERVFRD-1 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human ERVFRD-1 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ERVFRD-1 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human ERVFRD-1 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human ERVFRD-1 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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