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Vectors for Human GAD1

Gene Information

  • Offical Gene Symbol GAD1
  • Species Human (Homo sapiens)
  • Offical Full Name glutamate decarboxylase 1
  • Other Aliases CPSQ1; DEE89; GAD; SCP
  • Other Desigations glutamate decarboxylase 1; 67 kDa glutamic acid decarboxylase; GAD-67; glutamate decarboxylase 1 (brain, 67kDa)
  • Gene Type protein-coding
  • Summary
    This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form. [provided by RefSeq, Jul 2008]
  • NCBI Gene ID 2571
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human GAD1(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human GAD1 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human GAD1 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human GAD1 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human GAD1 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human GAD1 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human GAD1 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human GAD1 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human GAD1 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human GAD1 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human GAD1 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human GAD1 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human GAD1 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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